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ABX  advanced biochemical compounds   

Catalogue
Number 		Product Order number / Unit
1928 FFNP standard 1928.0010: 10 mg per vial
Please inquire for customized filling and bulk quantities.
 
Reference standard for [18F]FFNP
([18F]Fluoro furanyl norprogesterone)
Molar Mass: 428.49
C25H29FO5
[160388-33-0]
Colourless to off-white solid packaged in dark glass crimp cap vials.
Purity: > 95 %
Certificates:
CoA; 1H and 19F NMR spectra
Chemical Name:
CA index name: 19-Norpregn-4-ene-3,20-dione, 21-fluoro-16,17-[[(R)-2-furanylmethylene]bis(oxy)]-, (16alpha)-
Synonymes:
21-Fluoro-16α,17α-[(R)-(1'-alpha-furylmethylidene)dioxy]-19-norpregn-4-ene-3,20-dione; Fluoro Furanyl Norprogesterone; 16α,17α-[(R)-(1'-α-Furylmethylidene)dioxy]-21[fluoro]-oxy-19-norpregn-4-ene-3,20-dione; fluoro-19-norprogesterone-16α,17α-endo-furanyl acetal; 21-fluorofuranyl-norprogesterone; 19-Norpregn-4-ene-3,20-dione, 21-fluoro-16,17-[(2-furanylmethylene)bis(oxy)]-, [16α(R)]-; FFNP; [18F]FFNP standard
Literature:
Zhou D. et al. Optimization of the preparation of fluorine-18-labeled steroid receptor ligands 16α-[18F]fluoroestradiol (FES), [18F]fluoro furanylnorprogesterone (FFNP), and 16β-[18F]fluoro-5α-dihydrotestosterone (FDHT) as radiopharmaceuticals. J. Label. Compd. Radiopharm. 2014, 5, 371-377.
Vijaykumar D. et al. An Efficient Route for the Preparation of a 21-Fluoro Progestin-16alpha,17alpha-Dioxolane, a High-Affinity Ligand for PET Imaging of the Progesterone Receptor. J. Org. Chem. 2002, 67, 4904-4910.
Buckman B.O. et al. Fluorine-18-Labeled Progestin 16alpha,17alpha-Dioxolanes: Development of High-Affinity Ligands for the Progesterone Receptor with High in Vivo Target Site Selectivity. J. Med. Chem. 1995, 38, 328-337.
date of product catalogue issue: 10 May 2017

 
 
 

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