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Catalogue
Number
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Product
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Order number / Unit
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3358
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(+)-Flubatine precursor (GMP)
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Please inquire for customized
filling and bulk quantities.
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Precursor for (+)-[18F]Flubatine
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Manufactured according to GMP requirements for APIs for use in clinical trials (ICH Q7 chapter 19)
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Molar Mass: 473.39
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C20H32IN3O2
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CAS-RN not yet assigned
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White to yellowish solid packaged in dark glass vials.
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Purity:
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Certificates:
CoA with NMR and IR spectra, ESI-MS (identity); optical rotation; HPLC (purity); GC (residual solvents)
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Chemical Name:
5-((1S, 5R, 6R)-8-tert-butoxycarbonyl)-8-azabicyclo[3.2.1]octan-6-yl)-N,N,N-trimethylpyridin-2-aminium iodide
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Synonymes:
ABX126; (+)-Flubatine precursor; (+)-NCFHEB precursor; (+)-5-(8-tert-butoxycarbonyl)-8-azabicyclo[3.2.1]octan-6-yl)-N,N,N-trimethylpyridin-2-aminium iodide
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Literature:
Präkursorverbindungen für die Radiosynthese von [18F]Norchlor-fluor-homoepibatidin. Patent DE 2011080118062700
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Brust P. et al. In vivo measurement of nicotinic acetylcholine receptors with [18F]norchloro-fluoro-homoepibatidine. Synapse 2008, 62, 205-218.
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Deuther-Conrad W. et al. Norchloro-fluoro-homoepibatidine (NCFHEB) - a promising radioligand for neuroimaging nicotinic acetylcholine receptors with PET. Eur. Neuropsychopharmacol. 2008, 18, 222-229.
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Deuther-Conrad W. et al. Norchloro-fluoro-homoepibatidine: specificity to neuronal nicotinic acetylcholine receptor subtypes in vitro. Farmaco, 2004, 59, 785-792.
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date of product catalogue issue:
10 May 2017
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