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Catalogue
Number
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Product
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Order number / Unit
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3750
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CPTPX
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3750.0010: 10 mg per vial
Please inquire for customized
filling and bulk quantities.
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Precursor for [18F]CPFPX
8-Cyclopentyl-3-(3-[18F]fluoropropyl)-1-propylxanthine
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Molar Mass: 588.72
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C29H40N4O7S
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[478173-67-0]
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Colourless solid packaged in dark glass vials.
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Purity: > 95 %
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Certificates:
CoA; 1H NMR spectrum
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Chemical Name:
CA index name: Propanoic acid, 2,2-dimethyl-, [8-cyclopentyl-1,2,3,6-tetrahydro-3-[3-[[(4-methylphenyl)sulfonyl]oxy]propyl]-2,6-dioxo-1-propyl-7H-purin-7-yl]methyl ester
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Synonymes:
2,2-Dimethyl-propionic acid 8-cyclopentyl-2,6-dioxo-1-propyl-3-[3-(toluene-4-sulfonyloxy)-propyl]-1,2,3,6-tetrahydro-purin-7-ylmethyl ester; 8-Cyclopentyl-3-(3-tosyloxypropyl)-7-pivaloyloxymethyl-1-propylxanthine
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Literature:
Holschbach M. H. et al. Synthesis and Evaluation of No-Carrier-Added 8-Cyclopentyl-3-(3-[18F]fluoropropyl)-1-propylxanthine ([18F]CPFPX): A Potent and Selective A1-Adenosine Receptor Antagonist for in Vivo Imaging. J. Med. Chem. 2002, 45, 5150-5156.
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Bauer A. et al. Evaluation of 18F-CPFPX, a Novel Adenosine A1 Receptor Ligand: In Vitro Autoradiography and High-Resolution Small Animal PET. J. Nucl. Med. 2003, 44, 1682-1689.
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Matusch A. et al. Metabolism of the A1 adenosine receptor PET ligand [18F]CPFPX by CYP1A2: implications for bolus/infusion PET studies. Nucl. Med. Biol. 2006, 33, 891-898.
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Elmenhorst D. et al. Caffeine Occupancy of Human Cerebral A1 Adenosine Receptors: In Vivo Quantification with 18F-CPFPX and PET. J. Nucl. Med. 2012, 53, 1723-1729.
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date of product catalogue issue:
10 May 2017
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