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Catalogue
Number
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Product
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Order number / Unit
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5166
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O-Desmethyl Astemizole
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Please inquire for customized
filling and bulk quantities.
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Precursor for [11C]Astemizole and [18F]Fluoroethyl-astemizole
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Molar Mass: 444.54
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C27H29FN4O
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[73736-50-2]
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Colourless to off-white solid packaged in dark glass screw cap vials or dark glass crimp cap vials.
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Purity: > 95 %
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Certificates:
CoA; 1H and 19F NMR spectra
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Chemical Name:
4-[2-[4-[[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]amino]-1-piperidinyl]ethyl]phenol
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Synonymes:
O-desmethylastemizole; 4-(2-{4-[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-ylamino]-piperidin-1-yl}-ethyl)-phenol; [11C]Astemizole precursor; [18F]Astemizole precursor
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Literature:
Riss P. J. et al. Radiosynthesis and characterization of astemizole derivatives as lead compounds toward PET imaging of τ-pathology. Med. Chem. Commun. 2013, 4, 852-855.
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Cai L. et al. Synthesis of [11C]astemizole as a lead candidate radioligand for imaging brain neurofibrillary tangles. Neuroimage 2010, 52, Supplement 1, S152-S153
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date of product catalogue issue:
10 May 2017
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